3-Chloropyridine-4-boronic acid

3-Chloropyridine-4-boronic acid - Names and Identifiers

Name	3-Chloro-4-pyridineboronic acid
Synonyms	3-Chloro-4-pyridineboronicacid 3-CHLORO-4-PYRIDINEBORONIC ACID 3-Chloropyridine-4-boronic acid 3-Chloro-4-pyridineboronic acid 3-CHLOROPYRIDINE-4-BORONIC ACID 3-CHLOROPYRIDIN-4-YLBORONIC ACID (3-Chloropyridin-4-yl)boronic acid 3-chloropyridin-4-yl-4-boronic acid chlorooxy(pyridin-4-yl)borinic acid 3-CHLOROPYRIDINE-4-BORONIC ACID HYDRATE Boronic acid, B-(3-chloro-4-pyridinyl)- 3-Chloro-4-pyridineboronic acid hydrate 3-CHLORO-4-PYRIDINEBORONIC ACID HYDRATE Boronic acid, (3-chloro-4-pyridinyl)- (9CI)
CAS	458532-98-4
InChI	InChI=1/C5H5BClNO2/c7-5-3-8-2-1-4(5)6(9)10/h1-3,9-10H

3-Chloropyridine-4-boronic acid - Physico-chemical Properties

Molecular Formula	C5H5BClNO2
Molar Mass	157.36
Density	1.41±0.1 g/cm3(Predicted)
Melting Point	95-97
Boling Point	329.6±52.0 °C(Predicted)
Flash Point	153.2°C
Water Solubility	Slightly soluble in water.
Vapor Presure	7.04E-05mmHg at 25°C
pKa	7.30±0.58(Predicted)
Storage Condition	Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.559

3-Chloropyridine-4-boronic acid - Risk and Safety

Risk Codes	R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection.
Hazard Note	Irritant

3-Chloropyridine-4-boronic acid - Introduction

3-Chloro-4-pyridineboronic acid is an organic compound with the chemical formula C5H5BClNO2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 3-Chloro-4-pyridineboronic acid is a white to pale yellow solid.
-Solubility: It has low solubility in water, but is soluble in common organic solvents such as methanol, ethanol and dimethyl sulfoxide.
-Melting point: Its melting point is between 140-145 degrees Celsius.

Use:
- 3-Chloro-4-pyridineboronic acid is a commonly used reagent in organic synthesis and can be used to synthesize various boron-containing organic compounds.
-It can be used as a ligand and catalyst to play a role in metal-catalyzed reactions.
- 3-Chloro-4-pyridineboronic acid can also be used as an intermediate in drug development and pesticide synthesis.

Preparation Method:
- 3-Chloro-4-pyridineboronic acid can be prepared by reacting pyridine with boron trichloride. The reaction process can be carried out in a basic medium, and the reaction is controlled at an appropriate temperature.

Safety Information:
- 3-Chloro-4-pyridineboronic acid may cause irritation to the eyes, skin, and respiratory tract. When using, avoid direct contact and ensure that you operate in a well-ventilated environment.
-During storage, 3-Chloro-4-pyridineboronic acid should be stored in a sealed container, away from fire and oxidizing agents, and avoid contact with strong acids or alkalis.

Last Update：2024-04-09 02:00:46